Kisspeptin-10 is a naturally occurring neuropeptide studied in preclinical neuroendocrine research for its role in GPR54 receptor binding and hypothalamic-pituitary signaling.
Kisspeptin-10 is a decapeptide fragment derived from the KISS1 gene product, one of the shortest bioactive fragments of the kisspeptin family retaining full receptor activity. CAS: 374675-21-5. Kisspeptin signaling has become a central focus of preclinical neuroendocrine research due to its position as a key upstream regulator of the reproductive hormone cascade.
Kisspeptin-10 acts as an agonist at GPR54 (KISS1R), a G-protein coupled receptor expressed on gonadotropin-releasing hormone (GnRH) neurons in the hypothalamus. Receptor activation triggers pulsatile GnRH release, which in turn stimulates the pituitary to secrete luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This positions Kisspeptin-10 as a research tool for studying the hypothalamic-pituitary-gonadal (HPG) axis at a point upstream of GnRH itself.
NuvoTide's Kisspeptin-10 is supplied as a lyophilized powder, HPLC verified to ≥99% purity, and should be stored at -20°C prior to reconstitution. All NuvoTide Research products, including Kisspeptin-10, are supplied strictly for in-vitro laboratory research purposes and are not intended for human or veterinary use, and are not FDA-approved.
For in-vitro research use only. Not for human or veterinary use.